A randomized controlled trial on triamcinolone versus saline impregnated merocel post endoscopic sinus surgery: Our experience in a tertiary care centre

Purpose To assess the potential benefit of impregnating Merocel (a non-absorbable nasal dressing) with a topical steroid solution, for use as direct and slow local delivery system steroids after sinus surgery to improve postoperative wound healing. Methods In this randomized controlled trial, 40 patients bilateral chronic rhinosinusitis polyposis were subjected functional endoscopic surgery. Following completion surgery, packs inserted in cavities infiltrated 4 mL triamcinolone (40 mg/mL) one cavity (treatment group) normal saline other (control group). Nasal removed on third day healing assessment was done Weeks 1, 2, 4, 12. The findings noted per Lund Kennedy (LKES) perioperative endoscopy (POSE) scores compared both sides. Results Significant (P < 0.05) improvement score crusting polyp at Week 12, edema discharge 1 but there no significant scarring any week. Overall, difference between treatment control arms statistically all visits except 4. Also, POSE 12 not Conclusion This study positively concludes that packed drug-soaked had less period overall much better saline-soaked packs.